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Similar content being viewed by others Background Lifestyle interventions can significantly reduce the risk of developing type 2 diabetes (T2DM) [1] with weight loss being the primary mediator of the reduction in risk [2]

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doi: 10.1038/nature13270 79 MadirajuA

Survodutide is also being studied in Phase 3 trials for the treatment of MASH

However, in IRI, the dual nature of lactate, providing a protective effect through energy supply while simultaneously promoting ferroptotic damage, poses significant challenges for its clinical application

[1] They knew if they could mimic the GLP-1 hormone, they could have a potential gamechanger for diabetes patients, but it took nearly three decades to perfect the process