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Poor health creates ceiling limiting best possible outcomes regardless of peptide quality or dosing

For the trial product estimand, continuous endpoint analyses were conducted using a mixed model for repeated measures with randomized treatment as a factor and baseline endpoint value as a covariate

Proc Am Assoc Thorac Surg:102, 2005

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Focused ultrasound enhancement An emerging approach uses low-intensity focused ultrasound to temporarily increase blood-brain barrier permeability in conjunction with intranasal administration