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With respect to dosage, the average reductions were: 2000 mcg: 71.5% (single data point) 1,000 mcg: 31.8% Although limited data are available for higher dosages, the findings support the efficacy of both oral and non-oral B12 formulations in modulating homocysteine levels

Harvard Health Publishing notes that intramuscular injections are particularly useful here and that untreated pernicious anemia can cause lasting nervous system damage

Diabetics who take metformin may have low B12 levels as a side effect of the drug

Consultation Recommended

That said, responsible use requires medical supervision

Frequently Asked Questions About B12 Injections Can I take a supplement instead