Targeting histone deacetylases for cancer therapy: from molecular mechanisms to clinical implications
Triple combination therapy with PD-1/PD-L1, BRAF, and MEK inhibitor for stage III-IV melanoma: a systematic review and meta-analysis
Emerging evidence suggests that autophagy may significantly contribute to the pathogenesis of PCOS ( Beyond follicular dynamics, autophagy is essential for maintaining normal oocyte and granulosa cell function, as well as modulating insulin signaling ( e.g ., IL-1, IL-18), thereby mitigating chronic inflammation
Samocha-Bonet also examined the effect of oral L-glutamine [25 g], whole protein low in glutamine (25 g), or water on the concentration of incretin hormones and insulin response in well-controlled T2DM patients and found that the first-phase insulin response and total GLP-1 were enhanced following the ingestion of both L-glutamine and protein
Modeling heart failure risk in diabetes and kidney disease: limitations and potential applications of transverse aortic constriction in high-fat-fed mice
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