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DNA Repair: NAD+ is a substrate for enzymes such as sirtuins and PARPs, which repair damaged DNA and maintain genomic stability

FDA reviewers cited weak evidence, poor characterization, differences between proposed and studied administration routes, and the availability of approved therapies for the conditions discussed

Often, that involves both medications and lifestyle change

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Ethics declarations Conflict of interest SC received lecture or consultancy fees from AstraZeneca, Boehringer Ingelheim, Eli Lilly, MSD, Novo Nordisk

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