In a phase 2 study, triapine, forming a potentially redox active iron complex and known to inhibit the M2 subunit of the ribonucleotide reductase, showed clinical activity when administered sequentially with fludarabine in patients with accelerated myeloproliferative diseases and secondary AML (157, 158)
Asgher M, Khan MIR, Anjum NA et al (2015) Minimising toxicity of cadmium in plants-role of plant growth regulators
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Ung Glutathione bao lu th ngng
In addition, chronic but not acute GSH depletion by buthionine sulfoximine (BSO) recapitulated the iron-induced phenotype
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