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Hepatic mRNA expression of Pygl , Gcgr , Igf1 , and Igf1r was indistinguishable between Dpp4 / and Dpp4 +/+ mice (Figure 1, E and F)
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Therefore, the identification of a set of pro- cells that contribute to the endogenous GLP-1 system supports the view that it is advantageous for islet cells to dedifferentiate to facilitate their survival
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