By cloaking synthetic nanoparticle cores with membranes derived from immune cells, these platforms inherit the surface receptor repertoire of the source cells, enabling them to evade immune clearance and actively target tumor tissues (54)
2k, the size of ATA@Cu NPs decreased from ~ 220 nm at pH 7.4 to less than 50 nm at pH 6.0, accompanied with the decomposition of ATA@Cu NPs at pH 6.0
On the contrary, activation of the TSS pathway under physiological cystine supplement is achieved under DMF treatment through enhanced CBS expression and cystine uptake to protect against ferroptosis in SCD erythroblasts
Neonate 79 , 172179 (2001)
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This aligns with our findings in the IIRI + LM mice model, in which Lactobacillus murinus treatment attenuated ferroptosis to preserve the intestinal barrier, further confirming the key role of Lactobacillus murinus in counteracting IIRI