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doi: 10.1038/s41467-021-21099-2 56 ZhaoLChengSFanLZhangBXuS

Conditioned media derived from CAV-1-silenced keratinocytes stimulated with either IL22, IL22 plus sCSD, or IL22 plus sB was added (1:3 with vascular cell basal medium) and cultured 4 h

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It is a once weekly subcutaneous injection and is available in doses that begin at 0.25 mg and titrate up to 2.0 mg

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Experimental application must remain within controlled, in vitro environments