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This guide explains what the evidence shows and how to make informed decisions about your sleep support

For some patients, particularly those with specific comorbidities or medication combinations, a provider may recommend semaglutide as the more clinically appropriate choice

Mild flushing or warmth shortly after dosing

however, all four participants with SAEs were in the placebo group, with the participant with SUSAR in the semaglutide group

Clin Gastroenterol Hepatol 2025;23:739-47.ArticlePubMed 22

SURMOUNT-1 Trial (72-Week Duration, 2,539 Participants): Average weight loss with 15 mg: 20.9% of body weight Participants losing 5%: 91% Participants losing 10%: 82% Participants losing 20%: 57% SURMOUNT-2 Trial (People with Type 2 Diabetes): Average weight loss with 15 mg: 15.7% A1C reduction: 2.0 percentage points Source: Jastreboff AM, et al