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Zeng L et al
Like many therapeutic peptides, epitalon is typically cycled, which means using the drug for a specific period and then taking a break from it
This is based on the role of SAM as both an allosteric activator of cystathionine -synthase and an allosteric inhibitor of MTHFR, the enzyme that produces 5-methyltetrahydrofolate (Figure 2)
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