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Key Characteristics Medication class GLP-1 & GIP/GLP-1 receptor agonists Active compounds Tirzepatide (Zepbound/Mounjaro-class) Semaglutide (Wegovy-class) Administration Weekly subcutaneous injection self-administered at home

CTA was quantified using Statistics Data were plotted using GraphPad Prism 10.6.1 software

Pancreatitis Warning: Patients should discontinue use if pancreatitis is suspected

Genetic mouse models for MAOB inhibition and overexpression We implemented procedures to establish the MAOB KD mouse model prior to the double-stress paradigm

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