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Semaglutide (Ozempic/Wegovy) Popular weekly GLP-1 injection that promotes fullness, reduces cravings, and helps burn stored fat
This inhibition of the mitochondrial respiratory chain leads to an increase in the production of hydrogen peroxide and superoxide (O 2 * - ) and oxygen radical species (Sakka et al ., 2003
Patients should seek care if they develop severe muscle pain or marked weakness that impacts daily function
Baseline characteristics before GLP-1 RA treatment including age, gender, duration of diabetes mellitus, body mass index (BMI), serum creatinine, alanine aminotransferase, fasting plasma glucose, glycohemoglobin (HbA1c), C-peptide, lipid profiles, urine albumin-to-creatinine ratio (UACR) and concurrent antidiabetic medication use were recorded
& Giorgino, F
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