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10.1002/ana.10616 Ann
Lowering GSH levels also triggers ferroptosis through deactivation of GPX4, leading to accumulation of lipid peroxides [87] In some cases, GSH depletion alone can induce therapeutic effects without relying on Fenton chemistry, which typically involves HO reacting with Fe 2 to form hydroxyl radicals (OH) that damage critical biomolecules such as DNA, proteins, and lipids
Individual results vary based on starting weight, metabolism, diet quality, and activity level
Molecular weight approximately 1419.53 Da
Protective effects of genistein on myocardial injury in diabetic rats
For histology, mouse livers were fixed in 4% paraformaldehyde in PBS at 4C for 24 h and then switched to 70% ethanol
