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But the official regulatory framework covers only the diabetes indication at this time

Search closed December 2024, Embase was not included, and risk of bias used NHLBI tools rather than Cochrane RoB 2 or ROBINS-I

This is the strongest peer-reviewed human evidence in the T4 family, although the formulation tested was full-length T4, not the TB-500 fragment used in commercial peptide products

Melanoma Res 2013

Canagliflozin reduced the risk of the primary composite outcome (ESKD, doubling of serum creatinine, or renal or cardiovascular death) by 30% compared to placebo, with consistent effects across all prespecified subgroups [46]

Thomas C, Pellicciari R, Pruzanski M, et al