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Among the modifiable risk factors for KOA, overweight and obesity are consistently regarded as the most important, influencing not only disease onset but also symptom burden, functional decline, and long-term therapeutic response (Gelber, 2024)
Purpose-built for physicians Preconception GLP-1 receptor agonist use may reduce pregnancy risks Key takeaways: GLP-1 receptor agonist use before pregnancy was tied to lower risks for hypertensive disorders of pregnancy and gestational diabetes
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Healthcare providers should counsel patients that fertility may improve during treatment, emphasizing the importance of reliable contraception
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