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This is a practical consideration rather than an evidence-based recommendation, and should be discussed with the prescriber or trial team

Various oxidative stress markers, including lipid peroxide [80], malondialdehyde [133], a marker of oxidative DNA damage 8-hydroxy-2-deoxyguanosine [119], and protein carbonyls [134, 135] are increased in ASD children

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This is the part that worries clinicians the most, and it is where most of the off-trial use is actually happening

Warning and Cautions: Do not exceed the recommended daily dosage