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Cell Death Dis
Absorption problems Even with adequate intake, absorption can be reduced by: Certain gastrointestinal conditions affecting the stomach or small intestine Some medications Age-related reduction in stomach acid (which can affect absorption) Autoimmune gastritis (often historically referred to as pernicious anaemia) This is a well-recognised cause of B12 deficiency and may require ongoing management
Vitamin B12 is absorbed in our body with the help of a protein produced in your stomach called the intrinsic factor
However, its longer shelf life and lower trash production often make up for its higher starting costs
Reported or proposed issue Long-term or repeated-cycle effects Evidence source No long-term human trial Known or theoretical
Dosing accuracy can vary
