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Importantly, leptin receptor knockdown did not yield changes in food-motivated behavior, while potent and lasting upregulation of food motivation was found here after GLP-1R knockdown, at least in males
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10.1016/j.ejmech.2024.117015 Eur
The intervention was delivered as single weekly intravenous infusion, with each dose administered over 15 min in 50 mL of saline, for two consecutive 8-week periods, separated by a 1-week washout
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