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doi: 10.1042/bsr20201273 251 WangWGuoPChenMChenDChengYHeL

Higher doses of retatrutide reduced biomarkers of insulin resistance, including fasting insulin, fasting C-peptide and HOMA2-IR, by up to 50% or more from baseline

DPP-4 inhibitors only modestly affect the levels of endogenous GLP-1, thus producing smaller glycemic reductions with minimal impact on weight reduction

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Researchers believe that hair loss during GLP-1 treatment is more related to underlying conditions than the drug itself