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Br J Clin Pharmacol 11(3):245250 Ryman JT, Meibohm B (2017) Pharmacokinetics of monoclonal antibodies
A meta-analysis of 13 clinical trials that included 421 patients with stage 25 CKD who did not require dialysis found that up to three months of exercise therapy resulted in a significant increase in eGFR compared with no exercise intervention
Initially described as a mediator of exercise-induced browning of white adipose tissue and increased energy expenditure, irisin was proposed as a candidate exercise- associated signaling molecule (Bostrm et al., 2012)
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