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Notably, RSL3 is widely used as a pharmacological inhibitor of GPX4, although studies in cell-free systems suggest that it may also exhibit inhibitory activity toward thioredoxin reductase 1 (TXNRD1), a key NADPH-dependent antioxidant enzyme that maintains thioredoxin-mediated redox homeostasis
That last point matters more than almost anything else in this guide
Its antioxidant properties help in reducing cellular damage and promote skin health
Glutathione helps protect neurons and supports healthy signaling
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