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Both substances affect overlapping physiological systems, particularly: Appetite regulation : Cannabis, particularly THC, is well known for stimulating appetite (colloquially termed "the munchies") by activating CB1 receptors in the hypothalamus and limbic system

The first GLP-1 drug was made by copying a chemical found in the venom of the Gila monster

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At ACR Convergence 2025, researchers from Toronto and NYU reported that PsA patients starting GLP-1 receptor agonists had significant improvements in joint counts, CRP, pain scores, and DAPSA disease activity scores within one year of treatment. Whats interesting is that you dont seem to need a large dose to see these benefits

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