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In April 2025, Novo Nordisk notified the FDA about several hundred units of counterfeit Ozempic in the U.S

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Increased Energy Expenditure Unlike treatments that mainly focus on appetite suppression, Retatrutides glucagon activity is being studied for its potential to increase energy expenditure

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"Prolonged stimulation of GH and IGF-1 secretion by CJC-1295 in healthy adults." J Clin Endocrinol Metab

Possible reasons include: Dehydration Fluid loss can trigger headaches