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GLP-1 and GIP are colocalized in a subset of endocrine cells in the small intestine

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Studies suggest this dual approach produces a 3-5 fold increase in growth hormone release compared to either peptide alone, while maintaining natural pulsatile secretion patterns

"Repurposing drugs already approved for other conditions has the advantage of providing data and experience from previous research and practical use so we already know a lot about real-world effectiveness in other diseases and side effects," Carrillo added

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