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Recent evidence suggests that oxidative stress may also promote life expectancy [3, 4]

Besides, infusion of exendin-4 into the 4th ventricle reduced food intake through reducing meal frequency in rats (57)

PMID 8845153

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Heidenreich PA, Trogdon JG, Khavjou OA, Butler J, Dracup K, Ezekowitz MD, Woo YJ: Forecasting the future of cardiovascular disease in the United States a policy statement from the American heart association