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In addition to SCFAs, other microbial metabolites are involved in the regulation of carbohydrate metabolism, and they probably play a role in the pathogenesis of diabetes

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Effet bnfique sur le mtabolisme nergtique, grce la vitamine B6

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The question of whether the increased cardiac workload (both rate and force) could cause long-term cardiac remodeling remains open

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Although the hypotensive effect of GLP-1 RAs seems to be manifested by BW losing, other mechanisms not related to BW might be implied by the mediation meta-analysis, which suggests an existence of BW-independent hypotensive effect of GLP-1 RA, along with the clinical evidence of weak or no correlations, and difference in time course between BP lowering and BW reducing effects

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