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Semaglutide lowers glucose levels , which is helpful for people with type 2 diabetes, but it can also raise the risk of hypoglycemia if combined with other medications like insulin or sulfonylureas

A 2023 observational study found that patients on GLP-1 therapy maintained 60% of their weight loss two years after treatment initiation, whereas phentermine users retained less than 20% of losses after stopping the drug

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2021 Jul 17;398(10296):212 )

Acknowledgements We thank all the laboratory members for helping with reading and commenting on the manuscript

Phentermine is a prescription appetite suppressant that is sometimes combined with other weight loss treatments like Tirzepatide or Mounjaro and Zepbound to enhance results