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Wirkung GLP-1-RA GLP-1-RA sind synthetische Polypeptide, die die Wirkung des krpereigenen GLP-1 imitieren, indem sie an GLP-1-Rezeptoren in Organen wie u
Cortese, S., & Tessari, L
More recently, a phase 2 trial published in the New England Journal of Medicine showed that high-dose semaglutide (2.4 mg weekly) achieved NASH resolution without worsening of fibrosis in 59% of patients versus 17% with placebo
Chemists developing small-molecule GLP-1s note that they are easier to manufacture and have better absorption profiles than peptides
A subset of patients find that their body's response plateaus on tirzepatide after initial success, or they achieve their goal weight and seek a maintenance-phase medication with potentially milder side effects
Symptoms of an allergic reaction include rash, itching, swelling, severe dizziness, and/or trouble breathing
