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Other antioxidants useful in counteracting OS renal damage are N-acetyl cysteine, ascorbic acid, L-carnitine, coenzyme Q10, curcumin, and resveratrol (119)
Specificity of isozymes of murine hepatic glutathione S-transferase for the conjugation of glutathione with L-phenylalanine mustard
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The identification, solubilization, and characterization of microsome-associated glutathione S-transferases
Multiple mechanisms contribute to this close relationship, including 18,19 : Endothelial dysfunction Volume overload and salt retention Overactivity of the sympathetic (fight-or-flight) nervous system Adverse changes in the hormonal regulation of blood pressure Dysfunction of the renin-angiotensin-aldosterone system Ultimately, in people with CKD and diabetes, kidney tissue and blood vessels are much more sensitive to pressure damage than those with uncomplicated mild-to-moderate high blood pressure
Used well, that can help close a gap
