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Importantly, this region contributes much less to receptor binding than to binding-protein binding, which is what makes the modification useful: it separates the two interactions rather than weakening both
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A recent study in mice, however, suggests that it may affect the gut
Written informed consent was obtained from all participants
Computational and Theoretical Chemistry , 1227, 114227
Moreover, this molecule showed a promising hepatoprotective function in a murine model of acute liver injury (32)
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