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The practical implication is that poor early response is uncommon and doesnt necessarily predict poor ultimate outcomes

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Physicians can still prescribe compounded semaglutide and tirzepatide, but after May 2025, they will only be able to prescribe brand-name versions like Ozempic, Wegovy, or Mounjaro

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The SELECT Trial: Design and Key Findings The SELECT trial enrolled 17,604 patients aged 45 or older with a BMI of 27 or greater and established cardiovascular disease (prior heart attack, stroke, or symptomatic peripheral artery disease), but critically, none had diabetes .[1] This design was intentionalresearchers wanted to understand whether semaglutide's cardiovascular benefits extended beyond its known effects in diabetic populations

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Mitigating the risks of compounded semaglutide Choosing a reputable pharmacy Choose a reputable compounding pharmacy that adheres to strict quality control standards

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These drugs offer support and can be a game changer where traditional methods may have failed, but they arent a one-size-fits-all solution

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