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( A C) Acta1 , Col3a1 , and Fn1 mRNA expression in H9c2 cells treated with MC1-R, MC3-R, MC4-R, or MC5-R selective agonist (10 nM for all agonists) for 3 h
This effect is possible due to its broader melanocortin receptor activity (notably MC3R and MC4R)
These results are consistent with previous studies [30, 39]
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By stimulating insulin secretion, inhibiting glucagon release, and slowing gastric emptying, semaglutide helps regulate blood sugar levels and promotes a feeling of fullness, thereby aiding in weight management
10.3892/etm.2019.7347 107 WangL.LiP.TangZ.YanX.FengB
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