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Other common digestive side effects include: Vomiting: Often occurs alongside nausea, especially when starting treatment Diarrhea: Usually mild and temporary Constipation: Can occur as your digestive system adjusts Stomach pain: Typically mild and manageable Loss of appetite: While this contributes to weight loss, it can be concerning for some patients These digestive effects happen because GLP-1 slows how quickly food moves through your stomach

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Thom E (2007) The effect of chlorogenic acid enriched coffee on glucose absorption in healthy volunteers and its effect on body mass when used long-term in overweight and obese people

There is no generally effective treatment, partly because of the large number of underlying causes