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MPGES1 have a key role in inflammatory diseases and is high upregulated in tissues during inflammation and overexpressed in tumors 23
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GIP receptors are present on immune cells, and GIP itself has demonstrated immunomodulatory properties in laboratory studies
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Second, our results suggest that the incorporation of halogen groups in the design of novel therapeutic agents could be a promising strategy to improve their pharmacological properties and aid in the development of more potent and selective MRPs inhibitors
Type 3 cytokines IL-17A and IL-22 drive TGF--dependent liver fibrosis
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