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In GLP-1R-MIN-6 cells, a high glucose (20 mM) level in the basal Gs activation state or 80 nM GLP-1 with a high glucose level stimulated insulin secretion, which was inhibited by H-89 and/or ESI-09

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Combined training and hormones/enzymes with insulinotropic actions in individuals with overweight and type 2 diabetes mellitus: A randomized controlled trial