(Clin Transl Med, 2021) in 24 older adults (aged 61-80) found that supplementation with GlyNAC (glycine 100 mg/kg/day + NAC 100 mg/kg/day, approximately 7 g each for a 70 kg person) for 16 weeks corrected glutathione deficiency and improved multiple hallmarks of aging including oxidative stress, mitochondrial dysfunction, inflammation, insulin resistance, endothelial dysfunction, body composition, exercise capacity, and cognition [10]
P.CoetzeeG
J Cardiovasc Pharmacol
Non-cognitive behaviours in an APP/PS1 transgenic model of Alzheimers disease
Longer term For longer repeated exposure, copper-related labs may be reviewed periodically with a clinician
Aside from its production in the liver, glutathione is also found in various dietary anti-aging supplements and plant food sources, including avocados, papaya, and brown rice