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Histone deacetylases (HDACs): Evolution, specificity, role in transcriptional complexes, and pharmacological actionability

Carnitine acetyltransferase (CrAT) can act as safety valve to catalyze the reversible transfer of acetyl groups between acetyl-CoA and acetylcarnitine, promoting the combination of excess acyl groups with carnitine, increasing the membrane permeability of these products and thus removing them from the mitochondria, allowing acylcarnitine to be formed in the mitochondrial matrix and exported to the plasma [7]

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The effect of propionyl L-carnitine on skeletal muscle metabolism in renal failure