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How the calculator works The calculator uses a cubic Hermite spline model fitted to published clinical trial data

[1] These medications include semaglutide (Ozempic, Wegovy), dulaglutide (Trulicity), liraglutide (Victoza, Saxenda), and tirzepatide (Mounjaro, Zepbound)

Two commonly referenced comparison compounds are semaglutide and tirzepatide, which represent single receptor and dual receptor incretin agonist designs respectively