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Other safety variables, including laboratory assessments and vital signs, are reported in ESM Table 5

sermorelin influences how the body partitions that deficit between fat and lean tissue

Factors that likely influence individual response include baseline heart rate, cardiovascular fitness level, autonomic nervous system tone, body composition, and potentially genetic variations in glucagon receptor density or sensitivity

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Fiber: Constipation is common on GLP-1s, and low fiber is often the culprit

It also provides the most sustained energy release of any macronutrient and supports neurotransmitter production that affects mood and mental clarity