Why they matter: Large randomised cardiovascular and renal outcome trials (EMPA-REG OUTCOME, DAPA-HF, DAPA-CKD, EMPEROR-Reduced/Preserved, CREDENCE, EMPA-KIDNEY) consistently showed reductions in heart-failure hospitalisation, progression of chronic kidney disease, and cardiovascular death
Elevated GH and IGF-1 axis activity is documented to correlate with cellular regeneration markers in laboratory repair models
The market is projected to expand at a compound annual growth rate (CAGR) of 10.06% between 2025 and 2034
The most common side effects of GLP-1s may include: nausea, diarrhea, vomiting, constipation, stomach (abdomen) pain, headache, tiredness (fatigue), upset stomach, dizziness, feeling bloated, belching, gas, stomach flu, and heartburn
Its found in onions, apples, garlic, and elderberries, and can help stabilize mast cells and reduce inflammation
Maturation skews macrophage polarization from M1 to M2 (interleukin-4 [IL-4], interleukin-10 [IL-10], IL-12, Arginase 1 [Arg-1]