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Animal data suggest subcutaneous routes required substantially higher doses than intravenous in rabbits, 1 mg/kg subcutaneous versus 25 mcg/kg IV, a 40-fold difference

The current sample spanned a wide age range (778 years), which enhances generalizability, but also introduces developmental heterogeneity

High-sensitivity GaAsP detectors are installed in the FV3000, allowing the detection of faint fluorescence signals with high signal-to-noise ratios

Within the liver tissue, inflammation-related pathways and metabolic remodeling of lipid and amino acid breakdown are triggered, of which the NADP/NADPH redox pathways may be the central regulator [18, 19]

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