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Indian regulators will scrutinise pharmacokinetic variability [how consistently the drug is absorbed in Indian bodies, given differences in diet, gut biology and genetics] in Indian populations," he says

This is a legal requirement, and the trial investigators are responsible for reporting serious adverse events to the relevant regulatory authorities

They stimulate insulin secretion and inhibit glucagon secretion by elevating endogenous GLP-1 concentrations without an intrinsic hypoglycaemia risk

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At 5,000 mcg/mL, stepping from 250 mcg to 500 mcg simply moves the draw from 5 units to 10 units