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Over time, regular IV glutathione may help even skin tone and reduce hyperpigmentation

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Nevertheless, the pooled analysis of 16 trials suggested improvements in the summary measure of patients' global functioning (assessed with the Clinical Global Impressions [CGI-I] scale) after 12 and 24 weeks of (but not after 52 weeks) of ALCAR treatment (1-3 g/day) and in cognitive performance (assessed with the Mini-Mental State Examination [MMSE] scale) after 24 weeks (but not at 12 or 52 weeks) (104)

doi:10.1093/jn/137.12.2809

doi:10.1007/s00213-024-06735-1

A 2018 review (9) also found that IV glutathione therapy and injections could cause the following, rare effects as well: Skin rashes Stevens-Johnson syndrome, a rare but serious disorder that affects mucous membranes