The regulator said it conducted an independent assessment of the potential association between GLP-1 RAs and NAION, but found available evidence was conflicting and sought advice from the national advisory committee on medicines on whether the evidence required additional risk-mitigation measures
Al-Aly emphasizes that the risk reduction is modest, but in the absence of a proven effective treatment, this is definitely welcome news and a big deal, and one that researchers will continue to study
Once-weekly IcoSema versus multiple daily insulin injections in type 2 diabetes management (COMBINE 3): an open-label, multicentre, treat-to-target, non-inferiority, randomised, phase 3a trial
If you have a high fever or severe GI distress, take note of when these symptoms started
While effective for pain relief, long-term opioid use can lead to adverse effects, including immunosuppression and neurohormonal deficiencies 59,60
In general, fees apply to handling CEP applications, revisions or renewals and for offering technical advice (where applicants seek scientific or regulatory guidance).In March 2026, the EDQM introduced two new guidelines aimed at accelerating CEP assessments
