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The four PDE5i currently approved in both Europe and the United States, and used with variable dosages and formulations, display different pharmacokinetic profiles enabling tailored treatment of ED based on patients requirements

Rights and permissions About this article Cite this article Yamamoto, E

10.7759/cureus.6073 Cureus

doi: 10.1203/00006450-200008000-00021 25

In human studies, hexarelin at approximately 1 to 2 mcg/kg IV produced plasma GH peaks that were among the highest of any synthetic secretagogue tested at that time, with Ghigo et al