Over time, deficiencies in iron, vitamin B12, vitamin D, or other nutrients can develop, contributing to fatigue
Additionally, several key clinical trial readouts delivered compelling data across multiple indications, for example (see Figure 1): Semaglutide : STEP-HFpEF (functional benefits in HFpEF), STEP-9 (pain reduction in knee osteoarthritis), STEP-10 (reversion to normoglycaemia in pre-diabetic, obese patients), ESSENCE (resolution of MASH, improvement in fibrosis) Tirzepatide : SUMMIT (risk reduction in HFpEF outcomes
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Novo Nordisks oral semaglutide, Rybelsus, employs both co-formulation and clever biochemical engineering of the drug molecule itself to move us closer to this goal
Korinn Saker is a board-certified veterinarian and a retired professor of clinical nutrition at the College of Veterinary Medicine, North Carolina State University