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This reduction in GSH synthesis may contribute to excessive oxidative stress in infants

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Barlogie B, Raber MN, Schumann J, Johnson TS, Drewinko B, Swartzendruber DE, Gohde W, Andreeff M , Freireich EJ

High doses of nicotinamide prevent oxidative mitochondrial dysfunction in a cellular model and improve motor deficit in a Drosophila model of Parkinsons disease