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No established scientific evidence shows that B12 supplementation directly causes anxiety

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Storage: Reconstituted peptide solutions should generally be stored in a refrigerator at 28C and protected from light Avoid freezing the reconstituted solution In-use shelf life must follow product-specific validated stability data

Individuals with gastrointestinal conditions affecting absorption require careful monitoring: Pernicious anaemia (autoimmune condition destroying intrinsic factor-producing cells) Crohn's disease or coeliac disease affecting the terminal ileum Following gastric surgery (gastrectomy or bariatric procedures) Chronic pancreatitis Small intestinal bacterial overgrowth (SIBO) People taking certain medications may experience impaired B12 absorption: Metformin (diabetes medication)the MHRA Drug Safety Update advises monitoring B12 levels in patients on long-term treatment, particularly those with anaemia or peripheral neuropathy [17] Proton pump inhibitors (PPIs) and H2-receptor antagonistslong-term use reduces stomach acid necessary for B12 release from food [18] [19] Nitrous oxide (anaesthetic or recreational use) can inactivate B12 in the body [9] [21] Pregnant and breastfeeding women , particularly those following plant-based diets, should ensure adequate B12 intake to support foetal and infant neurological development

B12 is a water-soluble vitamin that aids in metabolism, among other purposes such as red blood cell formation and nerve function

Another cause is due to the lack of foods that contain vitamin B12 in your diet