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SREBP1a and SREBP1c are preferentially involved in fatty acid biosynthesis, while SREBP2 mainly regulates genes in the cholesterol biosynthesis pathway [80]
Recent advances in the knowledge of cancer biology led to the development of a new diagnostic and therapeutic arsenal that is not limited to selective target drugs but also includes already existing drugs that are multi-targeted or used in polypharmacology (Gonzalez-Fierro and Dueas-Gonzlez, 2021)
In brief, animals ( n = 8 per group, per sex) were placed into individual cages at their standard temperature and photoperiod and allowed to acclimate for at least 72 h prior to the experiment, and data were collected over a 24 h period
Jacques emphasized that the supplement industry should continue to position products as support products for weight loss maintenance rather than drug alternatives, noting that the pharmaceutical industry is moving aggressively into maintenance and long-term obesity management
(Basel) 10 , 1458 (2021)